@Anonymous: First off, hugs. I too have big boobs: dress size 10, bra size 34G (aka DDDD). I was the only girl in 5th grade who needed a bra to run the mile. I'm 29 and they're still growing.
Weight loss doesn't affect my boobs either. When I started getting more fit two years ago, my band size dropped from 36 to 34 but my boobs actually got a cup size BIGGER. I went directly from 36DD to 34G, do not pass Go, do not collect $200. (Actually, go SPEND $200. On new lingerie.)
I strongly suggest you head over to the Reddit community dedicated to those of us with gazongas, and post your comment there:
It's a wonderfully supportive community. We laugh together, we cry together, and we all bust out of button-downs.